Cell- and animal-based models of bone formation reveal novel mechanisms involved in the cartilage-to-bone phenotype ...

A recent study identifies Neural EGFL-like 2 (NELL2), a secreted protein, as a key regulator of bone homeostasis, offering potential therapeutic applications for osteoporosis. NELL2 promotes ...

A newly discovered receptor switch that boosts bone growth could transform how we treat osteoporosis, by stimulating the body’s own bone-building machinery using a targeted drug and even mechanical ...

A recent study identifies Neural EGFL-like 2 (NELL2), a secreted protein, as a key regulator of bone homeostasis, offering potential therapeutic applications for osteoporosis. NELL2 promotes ...

Obesity is widely known for increasing the risk of diabetes and cardiovascular disease, but its damaging effects on the ...

Scientists have identified a protein that blocks the activity of bone-forming cells (osteoblasts) by stopping them from maturing during the journey to sites of bone formation, a new study has found.

As flare-ups often precede the formation of new lesions, we are encouraged that this investigational drug may help prevent the progression of FOP. "The loss of mobility created by the abnormal bone ...

A new small molecule could treat and prevent excess bone formation. Fibrodysplasia ossificans progressiva (FOP) is an extremely rare disease estimated to affect about one in 2 million people worldwide ...

A research team from the Department of Medicine, School of Clinical Medicine, LKS Faculty of Medicine at the University of Hong Kong (HKUMed) has uncovered a key biological mechanism that explains how ...

Studies by University of Birmingham researchers suggest that a naturally occurring peptide known as PEPITEM (Peptide Inhibitor of Trans-Endothelial Migration), could represent a promising potential ...