DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

A deeper understanding of how DNA changes over generations helps scientists learn why people differ and how diseases develop. Until recently, many fast-changing parts of the human genome remained ...

James Dewey Watson, whose co-discovery of the twisted-ladder structure of DNA in 1953 helped launch a revolution in biology and medicine, died Thursday at age 97. He died in hospice care after a brief ...

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...