With an increasingly profound understanding of the interplay between condensate biology and diseases, there is a poised acceleration of classical drug development processes, catalyzing breakthroughs ...

First-in-class condensate-modulating small molecule Development Candidate targeting pathogenic TDP-43 condensates.Restores global TDP-43 splicing ...

Dewpoint to create a large-scale condensate phenomics atlas to illuminate cellular drivers of HPV-associated diseasesFunded by the Gates ...

Researchers have identified a new class of RNA molecule, called smOOPs, which support cellular phase separation, where macromolecules form biomolecular condensates that are critical for cell function.

Chemidroplet is a chemical tool, that fused the BTB-containing domain to the multivalent DNA binding domain (DBD) and intrinsically disordered regions (IDRs) to readily control the LLPS of these ...

A research group led by Professor Hiroaki SUZUKI and Takeshi HAYAKAWA from the Faculty of Science and Engineering at Chuo University, graduate student Zhitai HUANG, graduate students Kanji KANEKO (at ...