More than 50 years ago, cells were observed to die during insect development via a process that was named 'programmed cell death'. Later, a similar cell death process was found to occur in humans, and ...
Pyroptosis is programmed lytic cell death caused by the cleavage of gasdermin D by caspases 1, 4, 5 and 11. Recent work suggests that pyroptosis defends against infection by vacuolar or ...
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