Researchers are uncovering how disrupted glutamatergic synapses drive diverse forms of intellectual disability, revealing new ...
Representative cryo-electron microscopy image: a coloured image of the 3D structure of gephyrin, which was calculated from the data. A team of scientists from the University of Cologne’s Institute of ...
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How synapses stick together: Scientists discover brain protein gephyrin forms flexible filaments
A team of scientists from the University of Cologne's Institute of Biochemistry has made a decisive discovery about the molecular basis of synapse formation in the central nervous system. They studied ...
An analysis of how synaptic proteins change during early development reveals differences between mice and marmosets but also what's different in individuals with autism spectrum disorders. The ...
Figure 1. To observe dynamically changing synapses, dimerization-dependent fluorescent protein (ddFP) was expressed to observe flourescent signals upon synapse formation as ddFP enables fluorescence ...
The human brain contains nearly 86 billion neurons, constantly exchanging messages like an immense social media network, but neurons do not work alone – glial cells, neurotransmitters, receptors, and ...
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