A new two-photon fluorescence microscope developed at UC Davis can capture high-speed images of neural activity at cellular resolution thanks to a new adaptive sampling scheme and line illumination.

The microscope combines a big telecentric photolithography lens with a large tube lens to create sharp, detailed images of large and curved samples. These lenses project the image onto a flat array of ...

Metalenses represent a revolutionary advancement in optical technology. Unlike conventional microscope objectives that rely on curved glass surfaces, metalenses employ nanoscale structures to ...

When trying to measure molecular structures with nanometer precision, every bit of noise shows up in the data: someone walking past the microscope, tiny vibrations in the building and even the traffic ...

Electron microscopy is a powerful technique that provides high-resolution images by focusing a beam of electrons to reveal fine structural details in biological and material specimens. 2 Because ...

A classical way to image nanoscale structures in cells is with high-powered, expensive super-resolution microscopes. As an alternative, MIT researchers have developed a single-step technique for ...

Using a tiny, spherical glass lens sandwiched between two brass plates, the 17th-century Dutch microscopist Antonie van Leeuwenhoek was the first to officially describe red blood cells and sperm cells ...

In a study published in Science Advances, a team of bioengineering researchers at the University of Illinois Urbana-Champaign developed an algorithm known as adaptive intersection maximization, or AIM ...

Within a modest engineering laboratory at Duke University, a new type of researcher is quietly at work next to an optical microscope. This new researcher has no need for coffee, does not become tired, ...

Researchers have announced several major microscopy innovations that enhance resolution, sensitivity, and analytical capabilities for live biological imaging. Advances include AI-driven aberration ...