The CDC first recommended annual flu shots for all children 6 months and older in 2008, when it expanded the recommendation ...

A new randomised controlled trial has found promising evidence that the smoking cessation medication varenicline ...

The press release promoting the study asserts that “universal SEL programs are a sound investment in education systems ...

Randomized clinical trials remain the gold standard for establishing a medication's effects, producing the evidence by which ...

Introduction Each year, millions of people experience recurrent diverticulitis episodes. Elective sigmoid colon resection reduces the risk of recurrence, but The American Society of Colon and Rectal ...

Large language models could transform digestive disorder management, but further RCTs are essential to validate their ...

Randomized controlled trials (RCTs) are considered the gold standard for evaluating surgical interventions for benign prostatic hyperplasia (BPH). However, the validity and reliability of their ...

Objective Systemic corticosteroids for 5–7 days are standard care for asthma exacerbations, but the optimal duration and potential for precision prescribing remain unclear. Biomarker-guided approaches ...

Copyright: © 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies. Randomised controlled ...

Whether TNK (tenecteplase) benefits patients with acute ischemic stroke treated within 4.5 to 24 hours remains uncertain, and no previous meta-analysis has differentiated between clinical settings ...

Orforglipron, a small-molecule, nonpeptide oral glucagon-like peptide-1 (GLP-1) receptor agonist, is being investigated as a treatment for obesity. In this phase 3, multinational, randomized, ...

Aldosterone dysregulation plays an important pathogenic role in hard-to-control hypertension. In several studies, baxdrostat, an aldosterone synthase inhibitor, reduced the seated systolic blood ...